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Langmuir is the leading journal focusing on the science and application of systems and materials in which the interface dominates structure and function. Submissions on original advances in the understanding and particularly the rational design of interfaces, including novel concepts and emerging areas, are welcome. The following topics are examples within the scope of Langmuir. Surfaces and interfaces (synthetic and natural): adsorption, wetting, adhesion, forces and dynamics, surfactants, emulsions, foams, gels, and ultrathin films. Surface chemistry and forces of interface-rich systems and nanoparticles/colloids. Interface-driven stability: response, organization and self-organization of (nano)particle suspensions and structures, rheology and mechanics and non-equilibrium thermodynamics. Charge regulation and transfer at interfaces, electrochemistry, photocatalysis. Interfacial materials (synthesis/characterization) and processes for energy storage and transduction, and catalysis. Surface properties and applications of 1D, 2D and layered Van der Waals materials Single molecule and particle dynamics under confinement. Bio-interfaces: synthetic surfaces in vivo and in vitro, synthetic or membrane surface dynamics or biofouling, anti-microbial membrane interactions, and hydrophobic/hydrophilic interfaces. Transformed biointerfaces, such as nanocellulose and adaptive nanoparticles for drug delivery and diagnostics. Advanced surface and interface characterization techniques. Advanced microscopy. Theory & computations of interfacial properties.