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The first national gastroenterology Journal “Le Journal Belge de Gastro- Entérologie” was funded by Georges Brohée (first Editor-in-Chief) together with his colleagues Joseph Massion and Léon Daumerie in 1933. It was the official Journal of the Société Belge de Gastroentérologie. After the war, in 1946, the Journal was relaunched under its current name “Acta Gastro-Enterologica Belgica”. Since the launch of the Journal, the concept of diffusing scientific knowledge in the field of gastroenterology and hepatology has been well preserved for more than 80 years. Acta Gastro-Enterologica Belgica is now the official publication of the three following societies (Société Royale Belge de Gastro-Entérologie, Vlaamse Vereniging voor Gastro-enterologie and Belgian Week of Gastroenterology) and is published in partnership with eleven other Belgian scientific societies. Acta Gastro-Enterologica Belgica principally publishes peer-reviewed national and international original manuscripts, reviews, letters to the editors, expert points of view and guidelines in the field of clinical gastroenterology, hepatology, digestive oncology, digestive pathology, as well as clinical nutrition. Since 2020, Acta Gastro-Enterologica Belgica has become a fully open-access Journal in order to keep the Journal attractive in an interconnected world and in order to increase its visibility, to promote disease care and to facilitate communication within and between our scientific societies.