个人简述:

牙周炎与系统性疾病相关性研究，牙周炎一方面加重糖尿病、心血管疾病等全身病，一方面，在血脂血糖异常的情况下，机体容易患牙周炎。

科研工作:

[1] Ni J, Chen L, Zhong S, Chai Q, Zhang L, Wang D, Li S*, Zhang J*, Influence of periodontitis and scaling and root planing on insulin resistance and hepatic CD36 in obese rats. J Periodontol, 2018, 89(4):476-485. (IF 2018=3.392，JCR分区=2区)[2] Huang X, Yang X, Ni J, Xie B, Liu Y, Xuan D*, Zhang J*. Hyperglucose contributes to periodontitis: involvement of the NLRP3 pathway by engaging the innate immunity of oral gingival epithelium. J Periodontol, 2015, 86(2): 327-335. (IF 2015=2.706，JCR分区=2区)[3] Yang X, Zhang J*, Ni J, Ouyang B, Wang D, Luo S, Xie B, Xuan D. Toll-like receptor 4-mediated hyper-responsiveness of gingival epithelial cells to lipopolysaccharide in high-glucose environments. J Periodontol, 2014, 85(11): 1620-1628. (IF 2014=2.565，JCR分区=2区)[4] 钟素兰, 陈蕾, 柴巧学, 倪佳*, 李少冰*.非手术牙周治疗结合大黄素的应用对肥胖大鼠胰岛素抵抗及血清炎症因子的影响.实用医学杂志, 2018, 34(2): 188-190.[5] Luo S, Yang X, Wang D, Ni J, Wu J, Xu Z, Xuan D*, Zhang J*. Periodontitis contributes to aberrant metabolism in type 2 diabetes mellitus rats by stimulating the expression of adipokines. J Periodontal Res. 2016, 51(4): 453-461.（IF 2016=2.662，JCR分区=2区）