个人简述:

目前主持国家自然科学基金面上项目1项（NSFC81773745）和企事业横向合作课题多项，参与国家自然科学基金项目1项（NSCF81373419），曾主持国家自然科学基金青年项目1项（NSFC81202573）和中央高校基本科研业务业务费培育项目1项（PY2014YX0004）。截至目前，已发表中、英文学术论文共26篇（SCI收录21篇，EI收录1篇，国内核心期刊4篇），其中第一作者或通讯作者论文16篇；作为第三发明人申请发明专利 1项并获得授权。

科研工作:

部分代表作：1. Ao GZ, Zhou MZ, Li YY, Li SN, Wang HN, Wan QW, Li HQ, Hu QH*. Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents. Bioorg Med Chem25 (1): 166-174 (2017).2. Hu QH, Zhou MZ, Zhu H, Lu G, Zheng DS, Li HQ, Hao K. (E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1. Biomed Pharmacother86: 88-94 (2017).3. Wu H, Yuan YL, Chen YD, Lu G, Lan L, Yang ZL, Ji H, Hu QH*. Hypouricemic and nephroprotective effects of emodinol in oxonate-induced hyperuricemic mice are mediated by organic ion transporters and OIT3. Planta Med 82 (4): 289-297 (2016).4. Hu QH, Wei B, Wei L, Hua K, Yu X, Li H, Ji H. Sodium tanshinone IIA sulfonate ameliorates ischemia-induced myocardial inflammation and lipid accumulation in Beagle dogs through NLRP3 inflammasome. Int J Cardiol 196, 183-192 (2015).5. Li Q#,Hu QH#, Wang X, Zong Y, Zhao L, Xing J, Zhou J, Zhang H. Discovery of Novel 2-(piperidin-4-yl)-1H-benzo[d]imidazole Derivatives as Potential Anti-Inflammatory Agents. Chem Biol Drug Des86 (4), 509-516 (2015).6. Hu QH, Zhu JX, Ji J, Wei LL, Miao MX, Ji H. Fructus Gardenia Extract ameliorates oxonate-induced hyperuricemia with renal dysfunction in mice by regulating organic ion transporters and mOIT3. Molecules18(8): 8976-8993 (2013).7. Hu QH, Zhang X, Wang X, Jiao RQ, Kong LD. Quercetin regulates organic ion transporter and uromodulin expression and improves renal function in hyperuricemic mice. Eur J Nutr51 (5): 593-606 (2012).8. Hu QH, Zhang X, Pan Y, Li YC, Kong LD. Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats. Biochem Pharmacol84 (1): 113-125 (2012).

教育背景:

2002-2006年在南京大学匡亚明学院基础学科教学强化部学习获学士学位；2006-2011年在南京大学硕博连读并获博士学位。