个人简述:

张林，博士，副教授，硕士生导师。2014年入选“上海市浦江人才计划”。现任职于同济大学附属东方医院心衰研究所&心衰专科。2012年毕业于德国慕尼黑工业大学，以优异的成绩获得生命科学技术Ph.D博士学位。 同年于德国慕尼黑大学医院心内科从事博士后研究。参与了多项德国及欧洲的科研课题和国家自然科学基金项目，以第一作者或通讯作者在国际一流的医学期刊发表多篇学术论文，包括Circulation Research (影响因子 11.8)、 J. Exp. Med （影响因子13.214）、Blood（影响因子9.77）和心血管权威期刊Arteriosclerosis Thrombosis and Vascular Biology (影响因子6.338)等，期刊累积影响因子达52.822分。现为德国和欧洲心脏病学会成员, 《PLOSone》评委，国家自然科学基金评委

科研工作:

代表性文章（* 通讯作者）[1] Pi J#, Tao T#, Zhuang T#, Sun H, Chen X, Liu J, Cheng Y, Yu Z, Zhu HH, Gao WQ, Suo Y, Wei X, Chan P, Zheng X, Tian Y, Morrisey E, Zhang L*., Zhang Y*. A microRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability. Circ Res. 2016 Oct 18. pii: CIRCRESAHA.116.309757. [Epub ahead of print]；[2] Zhang L#, Orban M, Lorenz M, Barocke V, Braun D, Urtz N, Schulz C, von Brühl ML, Tirniceriu A, Gaertner F, Proia RL, Graf T, Bolz SS, Montanez E, Prinz M, Müller A, von Baumgarten L, Billich A, Sixt M, Fässler R, von Andrian UH, Junt T, Massberg S*. A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis. J. Exp. Med. 209(12):2165-81. Nov. 2012.；[3] Zhang L#, Urtz N, Gaertner F, Legate KR, Petzold T, Lorenz M, Mazharian A, Watson SP, Massberg S*. Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P). Aug. Blood. 122(5):791-802. 2013；[4] Zhang L#, Lukowski R#, Gaertner F, Lorenz M, Legate KR, Domes K, Angermeier E, Hofmann F, Massberg S*. Thrombocytosis as a Response to High Interleukin-6 Levels in cGMP-Dependent Protein Kinase I Mutant Mice. Arterioscler Thromb Vasc Biol. 33(8):1820-8. Aug. 2013；[5] Leierseder S#, Petzold T, Zhang L, Loyer X, Massberg S, Engelhardt S*. MiR-223 is dispensable for platelet production and function in mice. Thromb Haemost. 110(6): 1207-14. 2013；[6] Petzold T#, Ruppert R, Pandey D, Barocke V, Meyer H, Lorenz M, Zhang L, Siess W, Massberg S, Moser M*. β1 integrin-mediated signals are required for platelet granule secretion and hemostasis in mouse. Blood. 122(15):2723-31. 2013；[7] Mazharian A, Ghevaert C, Zhang L, Massberg S, Watson SP. Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation. Blood. 117(19). 2011。