个人简述:

池岛乔，男，博士，教授，博士生导师。1972年毕业于日本东北大学，获理学部生物学科学士学位，1974年于同校获理学研究科硕士学位，1978年获日本东北大学理学研究科博士学位。曾在日本横滨市立大学医学部、美国哈佛大学医学部、Tufts大学医学部任教，此后在日本万有制药株式会社（美国Merck公司的分公司）分子生物学研究所担任部长。1996年来到中国，在长春中医药大学担任教授，于2002年开始在沈阳药科大学任教。现为中日医药研究所所长。作为课题负责人主持了国家自然科学基金面上项目一项，作为主要参与人参与国家自然科学基金面上项目一项，辽宁省创新团队项目一项。在沈阳药科大学从事免疫药理学工作10余年来（2002年-），共发表相关论文约200篇（其中SCI收录189篇），学会发表论文约100篇（其中国际学会80余篇）。自2014年起，连续三年进入爱思唯尔高被引用学者榜单“药理学，毒理学和药剂学”学科前十名。迄今共培养博士研究生约40名、硕士研究生约60名，本科专题生约90名。

科研工作:

近年来发表代表性论文：1. Zheng, N., Liu, L., Liu, W., Li, F., Hayashi, T., Tashiro, S.-I., Onodera, S. & Ikejima, T.* (2017) Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro, Acta Pharmacol Sin. 38, 277-289.（IF=3.166）2. Wang, Y., Xu, L., Lou, L. L., Song, S. J., Yao, G. D., Ge, M. Y., Hayashi, T., Tashiro, S. I., Onodera, S. & Ikejima, T.* (2017) Timosaponin AIII induces apoptosis and autophagy in human melanoma A375-S2 cells, Arch Pharm Res. 40, 69-78.（IF=2.49）3. Song, X., Zhou, B., Cui, L., Lei, D., Zhang, P., Yao, G., Xia, M., Hayashi, T., Hattori, S., Ushiki-Kaku, Y., Tashiro, S. I., Onodera, S. & Ikejima, T.* (2017) Silibinin ameliorates Abeta25-35-induced memory deficits in rats by modulating autophagy and attenuating neuroinflammation as well as oxidative stress, Neurochem Res. 42, 1073-1083.（IF=2.472）4. Zheng, N., Liu, L., Liu, W., Zhang, P., Huang, H., Zang, L., Hayashi, T., Tashiro, S.-i., Onodera, S., Xia, M. & Ikejima, T.* (2016) ERbeta up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells, Arch Biochem Biophys. 591, 141-9.（IF=2.807）5. Zhang, T. G., Wang, Y. M., Zhao, J., Xia, M. Y., Peng, S. Q. & Ikejima, T.* (2016) Induction of protective autophagy against apoptosis in HepG2 cells by isoniazid independent of the p38 signaling pathway, Toxicol Res-Uk. 5, 963-972.（IF=2.161）6. Yao, G. D., Yang, J., Li, Q., Zhang, Y., Qi, M., Fan, S. M., Hayashi, T., Tashiro, S., Onodera, S. & Ikejima, T.* (2016) Activation of p53 contributes to pseudolaric acid B-induced senescence in human lung cancer cells in vitro, Acta Pharmacol Sin. 37, 919-29.（IF=3.166）7. Xu, Q., Liu, W., Liu, X., Liu, W., Wang, H., Yao, G., Zang, L., Hayashi, T., Tashiro, S.-I., Onodera, S. & Ikejima, T.* (2016) Silibinin negatively contributes to primary cilia length via autophagy regulated by histone deacetylase 6 in confluent mouse embryo fibroblast 3T3-L1 cells, Mol Cell Biochem. 420, 53-63. （IF=2.613）8. Wang, H. J., Li, M. Q., Liu, W. W., Hayashi, T., Fujisaki, H., Hattori, S., Tashiro, S. I., Onodera, S. & Ikejima, T.* (2016) Collagen gel protects L929 cells from TNFalpha-induced death by activating NF-kappaB, Connect Tissue Res, 1-8.（IF=1.411）9. Wang, H. J., Li, M. Q., Liu, W., Yao, G. D., Xia, M. Y., Hayashi, T., Fujisaki, H., Hattori, S., Tashiro, S., Onodera, S. & Ikejima, T.* (2016) Gelatin promotes murine fibrosarcoma L929 cell detachment and protects the cells from TNFalpha-induced cytotoxicity, Connect Tissue Res. 57, 262-9.（IF=1.411）10. Song, X., Zhou, B., Zhang, P., Lei, D., Wang, Y., Yao, G., Hayashi, T., Xia, M., Tashiro, S., Onodera, S. & Ikejima, T. * (2016) Protective Effect of Silibinin on Learning and Memory Impairment in LPS-Treated Rats via ROS-BDNF-TrkB Pathway, Neurochem Res. 41, 1662-72.（IF=2.472）