个人简述:

吴洁，教授，博士生导师。2004年获微生物与生化药学博士学位。2008-2010年在美国犹他大学医学院Fibrosis Research Lab进行访学研究。江苏省“333高层次人才培养工程”第三层次培养对象。微生物学会会员，Vaccine、Protein & Peptide Letters、《中国药科大学学报》、《药物生物技术》等审稿专家。主要从事糖尿病等自身免疫性疾病的发病机制及相关药物研究，先后主持或参与了多项国家自然科学基金、国家“863”、江苏省科技计划项目等。共发表SCI论文30余篇，获专利授权多项，获得省科技进步二等奖一项。

科研工作:

代表性论文：1.Lang J, Wang X, Liu K, He D, Niu P, Cao R, Jin L, Wu J*. Oral delivery of staphylococcal nuclease by Lactococcus lactisprevents type 1 diabetes mellitus in NOD mice. Appl Microbiol Biotechnol. 2017 Sep, 101:7653–622.Lili Shen, shiping Lu,Dongcheng Huang , Guoliang Li, Kunfeng Liu, Li Zong,Liang Jin*, Jie Wu*,Vaccination against type 1 diabetes with a novel peptide IA-2-P2 in streptozotocin-induced diabetic mice，Diabetes and Vascular Disease Research，2017 May14(3):184-190.3.Ma Y,Liu J,Hou J,Dong Y,Lu Y,Jin L,Cao R,Li T,Wu J*, Oral administration of recombinant Lactococcus lactis expressing HSP65 and tandemly repeated P277 reduces the incidence of type I diabetes in non-obese diabetic mice，PLoS One,2014 Aug 269(8) :1298-13024.Zhang J*, Wu J*, Gu C, Noble NA, Border WA, Huang Y. Receptor-mediated non-proteolytic activation of prorenin and induction of TGFss1 and PAI-1 expression in renal mesangial cells. Am J Physiol Renal Physiol. 2012 Jul303(1): 11-205.Jun L, Jie L, Dongping Y，Xin Y, Taiming Li, Rongyue C, Wu J*, Jingjing L, Effect of nasal immunization of multi-target preventive vaccines on atherosclerosis, Vaccine,2012,30:1023-316.Yong L, Huiyong Z, Jing H, Huaqian W, Xiangbing H, Yanjun M, Xiaoyu G, Li H, Yanan Y, Rongyue C, Hao F, Jingjing L, Jie W*.Vaccination with a potent DNA vaccine targeting B-cell epitopes of hGRP induces prophylactic and therapeutic antitumor activity in vivo.Gene Ther. 2010 Apr17(4):459-68.