个人简述:

吴英杰，博士，教授，博士生导师。 现任职于大连医科大学中西医结合研究院。1995年毕业于中国农业大学，获生物化学与分子生物学博士学位。同年赴美国，在宾夕法尼亚大学（University of Pennsylvania）从事博士后研究，1999任研究助理。2002年，任美国国立卫生研究院（National Institutes of Health）心肺血液研究所 Research fellow。2005年起，任职西奈山医学院（Mount Sinai School of Medicine)医学系研究副教授，2012年加盟大连医科大学中西医结合研究院，并兼任西奈山医学院Adjunct Associate Professor。到目前为止，已在包括The Journal of Clinical Investigation, Diabetes, Cancer Research, Endocrinology, Molecular Endocrinology, Journal of Bone and Mineral Research, Science 和 Cell等国际核心学术期刊发表四十余篇学术论文。

科研工作:

在研项目1. NIH/DDHS (AR054919)Title: The role of liver insulin-like growth factor 1 (IGF-1) in hepatocellular interactions
2. NIH/DDHS (5R01DK060612-09)Title: IGF and IGF Receptor Function in Mammary Development.
代表性文章1. Yingjie Wu, Chengyu Liu, Hui Sun, Archana Vijayakumar, Pejman Raeisi Giglou, Joshua Oppenheimer, Shoshana Yakar and Derek LeRoith. Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice. The Journal of Clinical Investigation 2011,121(6):2422–2426. SCI: 16.915
2. Archana Vijayakumar*, Yingjie Wu*, Chengyu Liu, Hui Sun, Shoshana Yakar and Derek LeRoith, Targeted loss of GHR signaling in mouse skeletal muscle protects from high-fat diet-induced metabolic deterioration, Diabetes 2012 ,61(1):94-103. (*Co-first authors). SCI: 8.889
3. Yingjie Wu, Pnina Brodt, Hui Sun, Wilson Mejia, Ruslan Novosyadlyy, Nomeli Nunez, Xiaoli Chen, Arnulfo Mendoza, Sung-Hyeok Hong, Chand Khanna and Shoshana Yakar. Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis. Cancer Research. 2010,70(1):57-67. SCI: 8.438
4. Yingjie Wu, Hui Sun, Shoshana Yakar, Derek LeRoith. Elevated levels of IGF-1 in serum rescue the severe growth retardation of IGF-1 null mice. Endocrinology 2009,150(9):4395-403. SCI: 5.103
5. Yingjie Wu, Chunxin Wang, Hui Sun, Derek LeRoith and Shoshana Yakar. High-Efficient FLPo Deleter Mice in C57BL/6J Background. PLoS ONE 2009, 4(11): e8054. SCI: 4.351.