个人简述:

孙立新，女，博士，教授。1989年毕业于沈阳药科大学，获药学学士学位，1997年于同校获药物分析硕士学位，2005年获同校药理学博士学位。1989年留校任教，先后被聘为沈阳药科大学助教、讲师、副教授、教授，现为药物分析系主任、国家级药学实验教学示范中心副主任、药物分析实验教学中心主任。作为课题负责人主持国家自然科学基金面上项目、国家十一五“重大新药创制”科技重大专项子课题、辽宁省自然科学基金、辽宁省科技厅重大项目、辽宁省高等学校创新团队资助项目等课题15项；作为项目骨干成员承担国家自然科学基金面上项目、国家 “重大新药创制”科技重大专项等课题20余项。目前已在Journal of Chromatography A, Journal of ChromatographyＢ, Journal of Pharmaceutical and Biomedical Analysis, journal of separation science,药学学报和中草药等期刊发表论文100余篇，其中SCI收载30余篇。

科研工作:

近年来发表代表性论文
1. Zhenxue Deng, Xiaobo Wang, Fang Wang, Zheng Qin, Yuqi Cui, Yangyang Sun, Lixin Sun*. Pharmacokinetics and tissue distribution study of 16-dehydropregnenolone liposome in female mice after intravenous administration. Drug Delivery，2016 23(8): 2787–2795.（SCI=4.843）2. Xiaonan Xu, Caifen Wang, Haiyan Li, Xue Li, Botao Liu, Vikramjeet Singh,Shuxia Wang, Lixin Sun*, Ruxandra Gref, Jiwen Zhang. Evaluation of drug loading capabilities of γ-cyclodextrin-metalorganic frameworks by high performance liquid chromatography. Journal of Chromatography A，1488（2017）:37-44. (IF= 4.712)3. Caifen Wang, Jingwen Ge, Jiwen Zhang, Tao Guo, Liandi Chi, Zhonggui He, Xu Xu, Peter York, Lixin Sun∗,Haiyan Li. Multianalyte determination of the kinetic rate constants of drug–cyclodextrin supermolecules by high performanceaffinity chromatography. Journal of Chromatography A, 1359 (2014) :287–295. (IF= 4.612)4. Jinwei Gao, Ying Qiu, Jinmei Chen, Shanxue Mu, Lixin Sun ∗. Simultaneous determination of nineteen major active compounds in Qiangshen tablet by UPLC-ESI-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 128 (2016) :519–527.（SCI=3.169）5. Sifei Liu, Guangrui Zhang, Ying Qiu, Xiaobo Wang, Lihan Guo, Yanxin Zhao, Meng Tong, Lan Wei, Lixin Sun*. Quality evaluation of Shenmaidihuang Pills based on the chromatographic fingerprints and simultaneous determination of seven bioactive constituents. journal of separation science . 2016, 39: 4557–4567.（SCI=2.741）6. Lan Wei, Xiaobo Wang, Shanxue Mu, Lixin Sun∗, Zhiguo Yu∗. Ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry coupled with hierarchical cluster analysis to evaluate Wikstroemia indica (L.) C. A. Mey. From different geographical regions. journal of separation science. 2015, 38: 2093–2100.（SCI=2.737）7. Cuichai Liu, Fang Wang, Xi Liu, Min Liu, Zheng Liu, Lixin Sun*. Based on Nucleotides Analysis of Tumor Cell Lines to Construct and Validate a Prediction Model of Mechanisms of Chemotherapeutics. Anti-Cancer Agents in Medicinal Chemistry , 2016, 16 (5) : 569-577.（SCI=2.722 ）8. Lan Wei, Xiaobo Wang, Peng Zhang, Yangyang Sun, Lili Jia, Jingxin Zhao,Shikai Dong, Lixin Sun∗. An UPLC–MS/MS method for simultaneous quantitation of two coumarins and two flavonoids in rat plasma and its application to apharmacokinetic study of Wikstroemia indica extract. Journal of Chromatography B, 1008 (2016) : 139–145.（SCI=2.687）9. Xi Liu, Chen-chen Zhang, Zheng Liu, Lan Wei, Yan-jie Liu, Jing Yu, Li-xin Sun*.LC-based targeted metabolomics analysis of nucleotides and identification of biomarkers associated with chemotherapeutic drugs in cultured cell models. Anti-Cancer Drugs. 2014, 25（6）: 690-702.（SCI=2.268 ）10.Yangyang Sun, Lili Jia, Hui Zhou, Mengqian Mao, Xiaobo Wang, Lan Wei，Lixin Sun*. Pharmacokinetics of 16-dehydropregnenolone hydroxypropyl-β-cyclodextrin inclusion complex following peroral administration. Pharmaceutical Development and Technology, 2017, 22（2）: 218-228.（SCI=1.566）