个人简述:

赵燕芳，女，博士，教授。1995年毕业于河北医科大学药学院，获药学学士学位；2001年获得沈阳药科大学药物化学硕士学位，2004年获同校药物化学博士学位，同年留校任教。2015年12月被聘为沈阳药科大学教授。现任制药工程学院副院长。作为课题负责人，共主持纵向项目5项：包括国家自然基金青年科学基金2项；国家重大新药创制科技重大专项1项，辽宁省重大新药创制综合平台子课题1项以及省级项目3项和沈阳市科技项目2项。共申请发明专利23项，其中申请PCT 7项,获得授权4项。发表研究论文35篇，其中SCI收载20余篇。2015年被评为辽宁省第九批“百千万人才工程”百人层次人选。2015年被评为沈阳药科大学优秀研究生导师。

科研工作:

近年来发表代表性论文
1. Hu, J, Kong B, Liu Y, Xu B, Zhao Y* Gong P* Highly Stereoselective Synthesis of Imidazolidines through the Palladium(0)-Catalyzed Three-Component Reaction of 2,3-Allenylamines, Organic Halides, and Imines. ChemCatChem, 2017, 9, 403-406. DOI: 10.1002/CCTC.201601345.(IF= 4.724)2. Xu B, Zhao Y, Wang X, Gong P* Ge W.* MZH29 is a Novel Potent Inhibitor that Overcomes Drug Resistance FLT3 Mutations in Acute Myeloid Leukemia. Leukemia, 2016, 1–9. (并列第一，IF=12.104)3. Liu M, Hou Y, Yin W, Zhou S, Qian P, Guo Z, Xu LY, Zhao Y.* Discovery of a Novel 6,7-Disubstituted-4-(2-fluorophenoxy)quinolines Bearing 1,2,3-Triazole-4-carboxamide Moiety as Potent c-Met Dinase Inhibitors. European J of Med Chem, 2016, 119, 96-108. DOI: 10.1016 /j.ejmech.2016.04.035(IF=3.902)4. Zhao Y Jiang M, Zhou S, Wu S, Zhang X, Ma L, Zhang K, Ping Gong*. Design, synthesis and Structure Activity Relationship of Oxazolidinone Derivatives Containing Novel S4 Ligand as FXa Inhibitors. European J of Med Chem, 2015, 96, 369-380(第一作者，IF=3.447)5. Wang F, Liu Z, Wang J, Tao J, Gong P, Bao X, Zhao Y*, Wang Y*. The interaction of 4-thiazolidinone derivatives containing indolin-2-one moiety with P-glycoprotein studied using K562 cell lines. European Journal of Medicinal Chemistry, 2015, 101, 126-132(双通讯,IF=3.447)6. Qin M, Wang T, Xu B, Ma Z, Jiang N, Xie H, Gong P*, Zhao Y*. Novel Hydrazone Moiety-bearing Aminopyrimidines as Selective Inhibitors of Epidermal Growth Factor Receptor T790M Mutant. European J Med Chem, 2015(4): 115-126(双通讯, IF=3.447)7. Liu Z, Wu S, Wang Y, Li R, Wang J, Wang L, Zhao Y*, Gong P*. Design, Synthesis and Biological Evaluation of Novel Thieno[3,2-d]pyrimidine Derivatives Possessing Diaryl Semicarbazone Scaffolds as Potent Antitumor Agents. European Journal of Medicinal Chemistry, 2014, 87: 782-793(双通讯, IF=3.432)8. Wang D, Zhao Y, Liu Z, Lei H, Dong M, Gong P*. In vitro and Intracellular Activity of 4-Substituted Piperazinyl Phenyl Oxazolidinone Analogues against Mycobacterium Tuberculosis. J Antimicrob Chemother, 2014, 12, 1711-1714（并列第一作者，IF=5.338）9. Tang Q, Zhang G, Du X, Zhu W, Li R, Lin H, Li P, Cheng M, Gong P, Zhao Y*. Discovery of Novel 6,7-Disubstituted-4-Phenoxy Quinoline Derivatives Bearing 5-(Aminomethylene) pyrimidine-2,4,6-trione Moiety as c-Met Kinase Inhibitors. Bioorganic & Medicinal Chemistry, 2014(22), 1236-1249. (通讯, IF=2.951)10. Zhou S, Liao H, Liu, Feng Guo, Fu B, Li R, Cheng M, Zhao Y*, Gong P*. Discovery and Biological Evaluation of Novel 6,7-Disubstituted-4-(2-fluorophenoxy)quinoline Derivatives Possessing 1,2,3-Triazole-4-carboxamide Moiety as c-Met kinase inhibitors. Bioorg Med Chem, 2014, 22: 6438–6452. (双通讯, IF=2.951)