个人简述:

田晓峰，1963年生人，医学博士，二级教授，博士生导师，校长助理，农工民主党党员。辽宁省特聘教授，辽宁省百千万人才百人层次，辽宁省重点学科带头人，辽宁省优秀人才支持计划获得者。大连市首批科技领军人才、大连市政府特贴、大连市劳动模范、大连市十大杰出青年获得者。中华医学会辽宁省外科分会常委、急腹症学组副组长，大连医学会常务理事，大连医师学会理事。先后获得国家科技部863课题1项、国家自然科学基金3项，以及省市各类课题20余项。发表文章110余篇，SCI收录51篇，总影响因子130。主编卫生部专科规划教材《外科学》和《实用普通外科手术学》等著作，参编本科规划教材《急症医学》及《现代外科理论与实践》等大型专著。获得国家专利技术1项，省科技进步二等奖1项，三等奖2项，大连市科技进步一等奖2项。培养毕业博、硕士研究生60余人。现任大连医科大学学报副主编，Would Journal of Hepatoloy、中华消化外科杂志、中国普外基础与临床杂志、世界华人消化杂志、中国医师进修杂志、中国实用外科杂志、中国普外基础与临床杂志、医学与哲学杂志等多个专业杂志的编委。

科研工作:

在研项目：1、2013年国家自然科学基金面上项目: Mir34a调控Sirt1-P66shc通路在肠缺血再灌注多器官损伤中的防止靶点研究(81372037)(2013 -2017) 70万
2、2012 国家教育部博士学科点专项基金: Sirt1通路在肠缺血再灌注多器官损伤发病机制中的核心作用及其防治靶点的研究 (20122105110001)(2012-2015) ，12万元
3、2012国家自然科学基金: p66shc通路在肠缺血再灌注多器官损伤发病机制中的作用及其防治靶点的研究 (81171850) 58万元
代表文章(责任作者)：1、Wang G, Yao J, Li Z, Zu G, Feng D, Shan W, Li Y, Hu Y, Zhao Y, Tian X*. miR-34a-5p inhibition alleviates intestinal ischemia/reperfusion induced ROS accumulation and apoptosis via activation of SIRT1 signaling. Antioxid Redox Signal. 2016, 24(17): 961-973. IF 7.4
2、Wei Xu, Yang Lu, Jihong Yao, Zhenlu Li, Zhao Chen, Guangzhi Wang, Huirong Jing, Xinyuan Zhang, Mingzhu Li, Jinyong Peng, Xiaofeng Tian*. Novel Role of Resveratrol: Suppression of HMGB1 Nucleocytoplasmic Translocation by the Up-Regulation of SIRT1 in Sepsis-Induced Liver Injury. Shock. 2014, 42(5): 440-447. IF 2.87
3、Zhe Fan, Huirong Jing , Jihong Yao , Yang Li, Xiaowei Hu, Huizhu Shao, Gang Shen, Jiyong Pan, Fuwen Luo, Xiaofeng Tian*. The protective effects of curcumin on experimental acute liver lesion induced by intestinal ischemia reperfusion through inhibiting the pathway of NF-κ B in a rat model. Oxidative Medicine and Cellular Longevity. 2014: 191624. IF 3.39
4、Guangzhi Wang, Zhao Chen, Feng Zhang, Huirong Jing, Wei Xu, Shili Ning, Zhenlu Li, Kexin Liu, Jihong Yao*, Xiaofeng Tian*. Blockade of PKCβ protects against remote organ injury induced by intestinal ischemia and reperfusion via a p66shc-mediated mitochondrial apoptotic pathway. Apoptosis, 2014, 19(9): 1342-1353. IF 3.949
5、Feng Zhang, Yan Hu, Xiaomei Xu, Xiaohan Zhai, Guangzhi Wang, Shili Ning, Jihong Yao, Xiaofeng Tian*. Icariin protects against intestinal ischemia/reperfusion injury through activation of SIRT1/FOXO3 pathway. Journal of Surgical Research, 2015, 194(1): 127-138. IF 2.02
6、Zhao Chen, Guangzhi Wang, Xiaohan Zhai, Yan Hu, Dongyan Gao, Lingfei Ma, Jihong Yao*, Xiaofeng Tian*. Selective Inhibition of Protein Kinase C β2 Attenuates the Adaptor P66Shc-Mediated Intestinal Ischemia-Reperfusion Injury. Cell Death Dis. 2014, 5: e1164. IF 6.044
7、Yan Hu, Feng Zhang, Xiaomei Xu, Xiaohan Zhai, Guangzhi Wang, Zhenhai Ma, Dongyan Gao, Xiaochi Ma, Qing Fan, Kexin Liu, Jihong Yao, Xiaofeng Tian*. SIRT1-mediated inhibition of p66shc expression alleviates liver ischemia/reperfusion injury. Critical Care Medicine, 2014, 42(5): e373-81. IF 6.37
8、Huirong Jing, Jihong Yao, Xingming Liu, Hui Fan, Feng Zhang, Zhenlu Li, Xiaofeng Tian*, Yun Zhou*. Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway. J Surg Res. 2014, 187(1): 252-261. IF 2.121
9、Xiaohan Zhai, Musen Lin, Feng Zhang, Yan Hu, Xiaomei Xu, Yubin Li, Xiaochi Ma, Xiaofeng Tian*, Jihong Yao*. Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells. Mol. Nutr. Food Res. 2012, 57(2): 249-259. IF 4.31
10、Wang GZ, Yao JH, Jing HR, Zhang F, Lin MS, Shi L, Wu H, Gao DY, Liu KX, Tian XF*. Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice. J Trauma Acute Care Surg. 2012, 73(5): 1130-1137. IF 1.97