个人简述:
徐晓军,男,1978年8月生,中国药科大学副教授,博士生导师。
科研工作:
主持科研项目情况:1.国家自然科学基金面上项目(81274159) 基于FOXO活性以及糖尿病果蝇模型的金芪降糖片活性组分分析 2.高等学校博士学科点专项科研基金(20120096120007)3.新世纪优秀人才支持计划(02431004)4.国家自然科学基金面上项目(81573637) 基于PPARγ-ApoE的酸枣仁抗阿尔茨海默症协同成分发现与作用机制研究
近年来代表性科研成果:1. Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells. Xu X, Zur Hausen A, Coy JF, Löchelt M. Int J Cancer. 2009 Mar 15124(6):1330-7.2. 6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.Hu R, Zhou P, Peng YB, Xu X, Ma J, Liu Q, Zhang L, Wen XD, Qi LW, Gao N, Li P.PLoS One. 20127(6):e39664.3. Insulin signaling regulates fatty acid catabolism at the level of CoA activation. Xu X, Gopalacharyulu P, Seppänen-Laakso T, Ruskeepää AL, Aye CC, Carson BP, Mora S, Orešič M, Teleman AA. PLoS Genet. 2012 Jan8(1):e1002478. doi: 10.1371/journal.pgen.1002478.4. Triptolide inhibits amyloid-β production and protects neural cells by inhibiting CXCR2 activity. Wang J, Shi ZQ, Xu X (通讯作者), Xin GZ, Chen J, Qi LW, Li P. J Alzheimers Dis. 201333(1):217-29. doi: 10.3233/JAD-2012-120841.5. Chemical Profiling of Jinqi Jiangtang Tablets by High-performance Liquid Chromatography Coupled with Electrospray Ionization Quadrupole Time-of-flight Tandem Mass Spectrometry Sun S, XIE ZS, LIU EH, YAN YT, XU X (通讯作者), LI P. Chinese Journal of Natural Medicines. 2014 Mar12(3):229-40.6. Antitumor activity of gemcitabine can be potentiated in pancreatic cancer through modulation of TLR4/NF-κB signaling by 6-shogaol. Zhou L, Qi L, Jiang L, Zhou P, Ma J, Xu X (通讯作者), Li P. AAPS J. 2014 Mar16(2):246-57.
教育背景:
2000/09-2008/06年,海德堡大学,生物系,博士研究生,获博士学位。2000/09-2004/06年,中国科学院上海分院,生化细胞所,研究生。1996/09-2000/06年,南京大学,生物科学与技术系,本科,获学士学位。