个人简述:

一直从事中药及其制剂的质量控制、中药药效物质基础等方面的研究。工作3年来，主持国家自然科学基金2项；江苏省自然科学基金、教育部博士点基金等科研项目5项，并参与国家科技重大专项等项目的研究。以第一作者或通讯作者发表论文10余篇，在中药现代化研究领域中具有较强的科研积累。

科研工作:

课题资助：（1）国家自然科学基金：翻白草中科罗索酸与所含三萜类成分协同调控巨噬细胞极化稳态系统抗2型糖尿病有效成分群的发现（批准号：81102763，主持）（2）国家自然科学基金：丹参地上部位调控巨噬细胞极化稳态抗动脉粥样硬化的物质基础及作用机制研究（批准号: 81373919, 主持）（3）教育部博士点基金：从巨噬细胞极化途径探讨民间药物翻白草总萜酮部位抗2型糖尿病的物质基础及作用机制（批准号：No. 20100096120004，主持）（4）江苏省自然科学基金：山绿茶抗非酒精性脂肪肝有效成分群的发现及其效应机制（批准号：BK2011627，主持）（5）国家自然科学基金：不同有效成分群组合效应研究山绿茶抗非酒精性脂肪肝药效物质基础及效应成分分析（批准号：81073039，参与）（6）中央高校基本科研业务费专项基金：基于代谢组学探讨山绿茶不同有效成分群抗非酒精性脂肪肝的效应关系及效应机制（批准号：JKQ2009008，主持）（7）天然药物活性组分与药效国家重点实验室优秀青年学者基金：基于多维液质联用技术研究山绿茶抗NAFLD有效成分群的体内过程及其资源的发掘（批准号：JKGQ201117，主持）
研究成果
1. Hong Chen,Jie Yang (Co- first author), Qin Zhang, Li-Hong Chen, Qiang Wang*. Corosolic Acid Ameliorates Atherosclerosis in Apolipoprotein E-Deficient Mice by Regulating the Nuclear Factor-κB Signaling Pathway and Inhibiting Monocyte Chemoattractant Protein-1 Expression. Circulation Journal. 76(4):995-1003,20122. Hong Chen, Qin Zhang, Xiaoming Wang, Jie Yang * (Co-corresponding author) and Qiang Wang*,Qualitative Analysis and Simultaneous Quantification of Phenolic Compounds in the Aerial Parts of Salvia miltiorrhiza by HPLC-DAD and ESI/MSn, Phytochemical Analysis, 22:247-257,20113. Jie Yang,Fang Lv, Xiao-qing Chen, Wei-xi Cui, Li-hong Chen, Xiao-dong Wen*, Qiang Wang*, Pharmacokinetic study of major bioactive components in rats after oral administration of extract of Ilex hainanensis by high-performance liquid chromatography/ electrospray ionization mass spectrometry.Journal of pharmaceutical and biomedical analysis 77:21-28,2013.4. Jie Yang, Xiao-dong Wen, Bei-xi Jia, Qian Mao, Qiang Wang*, Mao-xiang Lai. Quality evaluation of Potentilla discolor by high-performance liquid chromatography coupled with diode array detection and electrospray ionization tandem mass spectrometry. Phytochemical Analysis,22(6)547-554,20115. Jie Yang, Hong Chen, Li Zhang, Qiang Wang*, Mao-Xiang Lai. Anti-diabetic effect of standardized extract ofPotentilla discolorBungeand identification of its active components. Drug Development Research,71:127-132,20106. Rong-Hua Ma, Jie Yang (Co- first author),Lian-Wen Qi, Gui-ZhongXin, Chong-Zhi Wang, Chun-Su Yuan, Xiao-Dong Wen*, Ping Li*. In vivo microdialysis with LC–MS for analysis of spinosin and its interaction with cyclosporin A in rat brain, blood and bile. Journal of Pharmaceutical and Biomedical Analysis, 62: 22-29, 20127. Xiao-Dong Wen, Jie Yang (Co- first author), Rong-Hua Ma, Wen Gao, Lian-Wen Qi, Ping Li, Brent A. Bauer, Guang-Jian Du, Zhiyu Zhang, Jacqueline Somogyi, Chong-Zhi Wang, Chun-Su Yuan*, Analysis of Panaxnotoginsengmetabolites in rat bile by liquid chromatography-quadrupole time-of-flight mass spectrometry with microdialysis sampling, Journal of Chromatography B, 895-896:162-168, 2012.8. Li Zhang, Jie Yang (Co- first author), Xiao-qing Chen, Zanke, Xiao-dong Wen, Qiang Wang*, Mao-xiang Lai. Antidiabetic and antioxidant effects of extracts from Potentilla discolor Bunge on diabetic rats induced by high fat diet and streptozotocin. Journal of ethnopharmacology, 132(2):518-524,2010

教育背景:

2000.9—2004.7 中国药科大学中药学专业（本科） 学士；2004.9—2009.7 中国药科大学生药学（硕博连读）博士