个人简述:
郭兴杰,女,博士,教授。1982年2月毕业于沈阳药学院,获药学学士学位,1991年在沈阳药科大学获药物分析学硕士学位,2003年在沈阳药科大学获得药物分析学博士学位。2001年至2012年,在日本东京大学学习,完成了博士毕业论文的全部研究工作。2013年被聘为沈阳药科大学教授。作为课题负责人主持3项国家自然科学基项目,主持2项国家自然基金理科基础人才项目和2项科技部项目。另外,作为项目骨干成员承担国家自然科学基金面上项目1项,承担国家科技部项目1项。目前已在Talanta等SCI收载期刊发表论文40多篇。
科研工作:
近年来发表代表性论文:1. Linlin Fang, Ping Wang, Xiaoli Wen, Xin Guo, Linda Luo, Jia Yu and Xingjie Guo*. Layer-by-layer self-assembly of gold nanoparticles/thiols β-cyclodextrin coating as the stationary phase for enhanced chiral differentiation in open tubular capillary electrochromatography. [J].Talanta, 2017,167:158-165.(IF4.035)2. Xin Guo,Zhiqiang Wang,Lihua Zuo,Zhixu Zhou, Xingjie Guo*,Tiemin Sun*.Quantitative prediction of enantioseparation using β-cyclodextrin derivatives as chiral selectors in capillary electrophoresis.,Analyst,2014,139(24):6511-6519.(IF4.033)3. Linlin Fang,Jia Yu,Zhen Jiang and Xingjie Guo*. Preparation of a β-Cyclodextrin-Based Open-Tubular Capillary Electrochromatography Column and Application for Enantioseparations of Ten Basic Drugs. [J]. Plos One, 2016, 11(1):1-11. (IF3.057)4. Jinxia Wei,Linlin Fang,Xinlei Liang,Dan Su,Xingjie Guo *.A sensitive and selective UPLC–MS/MS method for simultaneous determination of 10 alkaloids from Rhizoma Menispermi in rat plasma and its application to a pharmacokinetic study. [J]. Talanta, 2015, 144:662-670. (IF4.035)5. (10) Jia Yu,Xinlei Liang,Zhaokun Wang,Xin Guo,Tiemin Sun,Xingjie Guo*.Separation of Folinic Acid Diastereomers in Capillary Electrophoresis Using a New Cationic β-Cyclodextrin Derivative. [J]. PLos One, 2015, 10(3):1-10. (IF3.057)6. Lihong Lin,Mingying Duan,Guang Chen,Xiaohong You,Changlin Liu,Xingjie Guo*. An LC-MS/MS method for determination of novel fungicide pyraoxystrobin in rat plasma and tissues: Toxicokinetics and tissue distribution study. [J].Talanta,2015, 136:183-189. (IF4.035)7.Jinxia Wei,Zhen Jiang,Zhi Cui,Xingjie Guo*. Rapid determination of eight oxoisoaporphine alkaloids in Rhizoma Menispermi by the optimal homogenate extraction followed by UPLC-MS/MS.[J].Analytical and Bioanalytical Chemistry, 2015, 407(18):5535-5540. (IF3.125)8. Xinlei Liang,Longshan Zhao,Miaoduo Deng,Lijie Liu,Yongfu Ma,Xingjie Guo*. Separation of Ofloxacin and Its Six Related Substances Enantiomers by Chiral Ligand-Exchange Chromatography.[J]. Chirality , 2015, 27(11):843-849. (IF2.025)9. Yan Cui,Zhen Jiang,Jiayi Sun,Jia Yu,Minghua Li,Mingjie Li,Mingxia Liu,Xingjie Guo *. Enantiomeric purity determination of (L)-amino acids with pre-column derivatization and chiral stationary phase: Development and validation of the method.[J].Food Chemistry, 2014, 158:401-407. (IF4.052)10. Lihong Lin, Wei Yu, Yanan Pang, Changsong Sun, Qinghe Meng, Xiaolei Li, Xingjie Guo*. Validation of an LC-MS/MS method for the quantitative determination of a novel fungicide: pyraoxystrobin in rat plasma and its application to a toxicokinetics study.[J].Analytical and Bioanalytical Chemistry, 2014, 406(22):5521-5526. IF3.125)