个人简述:

刘洁，女，1982年出生，药物化学专业博士，于2014年9月至2015年9月作为访问学者赴澳大利亚莫纳什大学进行为期一年的研究工作, 2015年晋升为副教授。先后主持国家自然科学基金青年项目1项，参与国家自然科学基金面上项目２项，国家重点实验室基金２项。

科研工作:

近年发表的主要论文：1.Chaolei Wang, Zheng Wu, Jia Wang, JieLiu,* Hequan Yao, Aijun Lin and Jinyi Xu*. An efficient synthesis of 4-isochromanones via Parham-type cyclization with Weinreb amide. Tetrahedron2015, 71, 8172-8177. 2.Chaolei Wang, Zheng Wu, Hao Cai, Shengtao Xu, Jie Liu,* Jieyun Jiang, Hequan Yao, Xiaoming Wu, Jinyi Xu*. Design, synthesis, biological evaluation and docking study of 4-isochromanone hybrides bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors. Bioorg. Med. Chem. Lett..2015, 25(22):5212-5216.3.Chaolei Wang, Guoxiang Wei, Yue Huang, Xue Yang, Hequan Yao, Jieyun Jiang, Jie Liu,*Mingqin Shen, Xiaoming Wu, Jinyi Xu*. First total synthesis of antihypertensive naturalproducts S-(+)-XJP and R-(−)-XJP. Organic&BiomolecularChemistry,2014,12(37):7338-44.4.Renren Baia, Xiaojing Huang, Xue Yang, Wen Hong, Yiqun Tang, Hequan Yao, Jieyun Jiang, Jie Liu, * Mingqin Shen, Xiaoming Wu,* Jinyi Xua. * Novel hybrids of natural isochroman-4-one bearing N-substitutedisopropanolamine as potential antihypertensive candidates.Bioorganic & Medicinal Chemistry, 2013, 21, 2495-2502.5.Rong Fu, Qiujuan Wang, Qinglong Guo, Jinyi Xu, Xiaoming Wu. XJP-1 inhibits expression of NADPH oxidase subunits and activates eNOS through PI3K/Akt pathway in HUVECs activated by ox-LDL. Vascular pharmacology, 201358:78-86 .6.Renren Bai , Xue Yang , Yao Zhu , Zhiwen Zhou , Weijia Xie , Hequan Yao , Jieyun Jiang , Jie Liu* , Mingqin Shen , Xiaoming Wu, Jinyi Xu* . Novel nitric oxide-releasing isochroman-4-one derivatives: synthesis and evaluation of antihypertensive activity. Bioorg. Med. Chem. 2012(20)6848-6855.

教育背景:

2004年本科毕业于中国药科大学理科基地专业，2009年获得中国药科大学药物化学专业博士学位。