个人简述:
主持完成“重大新药创制”国家重大科技专项(No.2009ZX09501)子课题项目研究。负责或参加多项横向研究课题,完成了膦甲酸钠、西吡氯铵、羟苯磺酸钙、硝呋呔尔和ONO-5046等药物的合成工艺或质量标准研究。主编学术著作和教材7本,在国内外学术刊物发表论文30余篇。
科研工作:
发表主要论著:1.YajingWang, Ping Lu, Weifeng Zhang, et al, GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-κB Pathway. Mediators of Inflammation, 2016, 1-17. http://dx.doi.org /10.1155 /2016/2853040.2.Hong Wang, YajingWang, Qianming Du, et al, Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cance rcells, Experimental Cell Research, 2016, 342: 184-192.3.Qianming Du, Yajing Wang, Chao Liu, et al, Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-beta-catenin axis, Oncotarget, 2016, 7: 17870-17884.4.Jingjing Tang, Xiaoting Geng, Yajing Wang, et al, Synthesis and cytotoxicity evaluation of 3-amino-2-hydroxypropoxyisoflavone derivatives, Chinese Journal of Natural Medicines, 2016, 14: 0462-0472.
教育背景:
1985年7月毕业于原南京药学院化学制药专业,2011年获中国药科大学药物化学专业博士学位。