个人简述:

吴春福，男，博士，教授。1982年毕业于沈阳药学院。2000年获日本北海道药科大学博士学位。分别于2002、2004、2006年赴美国哈佛大学、英国牛津大学、美国密歇根大学进修政府管理、教育管理等课程。1982年留校任教。1992年、1994年分别两次破格晋升为副教授、教授，1996年被评为博士生导师。1996年任沈阳药科大学常务副校长，2000年任校长，2010年任党委书记兼校长，2011年任校党委书记至今。为国家“十一五”重大新药创制综合平台辽宁省新药创制综合平台、国家中医药局重点研究室、辽宁省新药筛选实验室、辽宁省新药药效评价重点实验室的负责人。近年来先后主持了科技部“十一五”、“十二五”重大新药创制综合平台项目、国家自然科学基金、教育部青年骨干教师基金等重大课题的研究。已在Nature Nanotechnololgy, Proc. Natl. Acad. Sci. USA,Pharmacology Therapeutics,Cancer Letter, Free Radical Biology Medicine,Neurobiol.Aging等SCI期刊上发表文章近300余篇。

科研工作:

近年来发表代表性论文:1.Xue X1, Yang JY1,He Y1, Wang LR, Liu P, Yu LS, Bi GH, Zhu MM, Liu YY, Xiang RW, YangXT, Fan XY, Wang XM, Qi J, Zhan HJ, Wei T, Cui W, Ge GL, Xi ZX*, Wu CF*,Liang XJ*. Aggregated single-walled carbon nanotubes attenuate the behaviouraland neurochemical effects of methamphetamine in mice.Nature Nanotech,2016,11(7):613-20.(IF=35.267) (News and Views Nanomedicine: Goingsmall to beat the high by Dr. Eric C. Peterson & Laura E. Ewing)2.LiYT, Li HH, Liu X, Bao GB, Tao YZ, Wu ZY, Xia P, Wu CF, Li BM, Ma L.Regulation of amygdalar PKA by -arrestin-2/phosphodiesterase-4 complex iscritical for fear conditioning. Proc NatlAcad Sci USA. 2009,106(51):21918-21923. (IF=9.432)3.Xu NJ, Bao L, Fan HP, Bao GB, Pu L,Lu YJ, Wu CF, Zhang X, Pei G. Morphine withdrawal increases glutamateuptake and surface expression of glutamate transporter GLT1 at hippocampalsynapses. J Neurosci.2003,23(11): 4775-84. (IF=8.306)4.Yang JY, XueX, Tian H, Wang XX, Dong YX, Wang F, Zhao YN, Cui W, Wu CF*. Role ofmicroglia in ethanol-induced neurodegenerative disease: Pathological andbehavioral dysfunction at different developmental stages.Pharmacol Ther. 2014 ,144(3):321-372.(IF=7.745)5.Wang LH, Chen GL, Chen K, Ren Y, Li HH, Jiang XR, Jia L, Fu SY, Li Y, Liu XW, Wang S, Yang JY*, WuCF*. Dual targeting of retinoid Xreceptor and histone deacetylase with DW22 as a novel antitumor approach. Oncotarget,2015,6(12): 9740-9755. (IF=6.359)6.Wang FY, WangLH, Zhao YF, Li Y,Ping GF, Xiao S, Chen K, Zhu WF, Gong P*, Yang JY*,Wu CF*. A Novel Small-Molecule Activator of Procaspase-3Induces Apoptosis in Cancer Cells and Reduces Tumor Growth in Human Breast,Liver and Gallbladder Cancer Xenografts. Mol Oncol. 2014, 8(8):1640-52. (IF=5.935)7.Qi J, Han WY, Yang JY, Wang LH, Dong YX, Wang F, Song M, Wu CF*. Oxytocin regulateschanges of extracellular glutamate and GABA levels induced by methamphetaminein the mouse brain.Addict Biol. 2012,17(4):758-769. (IF=5.914)8.Tian H, YeXX, Hou XJ, Yang XW, Yang JY*, Wu CF*. SVCT2, a potential therapeutictarget, protects against oxidative stress during ethanol-induced neurotoxicityvia JNK/p38 MAPKs, NF-κB and miRNA125a-5p. FreeRadical Bio Med. 2016, 96:362-373. (IF=5.736)9.Li Y , Fu SY, Wang LH, Wang FY, WangNN, Cao Q, Wang Y T, Yang JY*, Wu CF*. Copper Improves theAnti-angiogenic Activity of Disulfiram Through the EGFR/Src/VEGF Pathway inGliomas. Cancer Lett .2015, 369: 86-96.(IF=5.621)10.Zhao SQ, Yang JY, Wang LX, Peng SY, Yin J, Jia LN,Yang XW, Yuan ZQ*, Wu CF*.NF-kappaB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells:Inhibition by Sildenafil and Yonkenafil. Mol Neurobiol. 201653(4):2647-2658. (IF=5.397)