个人简述:

胡海洋，男，博士，副教授。2000年毕业于沈阳药科大学，获药物制剂学士学位，2006年于同校获药剂学博士学位，2006年于沈阳药科大学药剂教研室任教，讲师，2013年被聘为沈阳药科大学副教授，硕士生导师，2016赴美国University of North Carolina at Chapel Hill进行访问学者研究。作为课题负责人主持了国家自然科学基金青年基金项目1项，辽宁省教育厅项目2项，另外，作为项目骨干成员承担国家自然科学基金面上项目3项。目前已在IJP，Biomaterial，Acta biomaterialia等期刊发表论文20余篇。

科研工作:

近年来发表代表性论文(限第一作者或通讯作者，SCI须写明影响因子)：1. LiW, Zhang X, Jing S, Xin X, Chen K, Chen D, Hu H*.Organic metal complexes based onzoledronate–calcium: a potential pDNA delivery system. J. Mater. Chem. B. 2017,5(8): 1601-1610. (IF=4.543)(通讯作者)2. Zhang M,Jing S, Zhang, Jiulong Zhang J, Zang X, Zhao X，Qiao X, Hu H* and Chen D. Intracellular release of PluronicL64 unimers into MCF-7/ADRcells to overcome multidrug resistance by surface-modified PAMAM. J. Mater.Chem. B2017,5, 3970-3981. (IF=4.543) (通讯作者)3. LiW, Zhang X, Jing S, Xin X, Chen K, Chen D, Hu H*. Preparation of CalciumPhosphate/pDNA Nanoparticles for Exogenous Gene Delivery by Co-PrecipitationMethod: Optimization of Formulation Variables Using Box-Behnken Design. J PharmSci, 2017,106 (8):2053-2059. (IF=2.713) (通讯作者)4.Chen K, Guo L, Zhang J, Chen Q, Wang K, LiC, Li W, Qiao M, Zhao X, Hu H*, Chen D.A genedelivery system containing nuclear localization signal: Increased nucleusimport and transfection efficiency with the assistance of RanGAP1. Acta Biomaterialia, 2017, 48:215-226. (IF=6.319) (通讯作者)5. zhang J,Liu D, Zhang M, Sun Y, Zhang X, Guan G, Zhao X, Qiao M, Chen D, Hu H*. The cellular uptake mechanism,intracellular transportation, and exocytosis of polyamidoamine dendrimers inmultidrug-resistant breast cancer cells. Int J Nanomedicine, 2016, 11:3677-90.(IF=4.3) (通讯作者)6.ChenK, Chen Q, Wang K, Zhu J, Li W, Li W, QiuL, Guan G, Qiao M, Zhao X, Hu H*, Chen D Synthesis and characterization of a PAMAM-OHderivative containing an acid-labile β-thiopropionate bond for gene delivery.International Journal of Pharmaceutics. 2016,509 (1–2): 314-327. (IF=4.3) (通讯作者)7. WangM, Hu H*, Sun Y, QiuL, Zhang J, Guan G, Zhao X, Qiao M, ChengL, Cheng L, Chen D. A pH-sensitive gene delivery system based onfolic acid-PEG-chitosan - PAMAM-plasmid DNA complexes for cancer celltargeting. Biomaterials,2013, 34（38）, 10120-10132. (IF=7.6) (通讯作者)8. Liu D, HuH*, Lin Z, Chen D, Zhu Y, Hou S, Shi X. Quercetindeformable liposome: Preparation and efficacy against ultraviolet B inducedskin damages in vitro and in vivo. J Photochem Photobiol B, 2013, 127, 8-17. (IF=3.11)(共同第一作者)9. Hu H*, LiuD, Zhao X, Qiao M, Chen D. Preparation, characterization, cellularuptake and evaluation in vivo of solid lipid nanoparticles loaded withcucurbitacin B. Drug Dev Ind Pharm,2013, 39 (5) :770-779. (IF=1.5) (第一作者)10. 顾莹熙，胡海洋*等.拟低密度脂蛋白脂质核心的制备及性质考察. 沈阳药科大学学报, 2014, 31(4): 241. (通讯作者)