个人简述:

刘亚婧，女，博士，副教授。2001年毕业于沈阳药科大学，获化学制药学士学位，2005年于同校获药物化学硕士学位，2008年于同校获药物化学博士学位，并留校任教至今。2013年受聘为沈阳药科大学副教授。作为课题负责人主持了国家自然科学基金1项，国家科技重大专项1项，省、市级科研项目3项。目前已申请发明专利20余项，其中PCT专利2项，获专利授权12项；已在J Cell Mol Med., Euro J Med. Chem., Bioorg. Med. Chem.等期刊发表论文28篇。

科研工作:

1. Wang F1, Liu Y,（双第一） Wang L, Yang J, Zhao Y, Wang N, Cao Q, Gong P, Wu C.Targeting procaspase-3 with WF-208, a novel PAC-1 derivative, causes selective cancer cell apoptosis. J Cell Mol Med. (IF=4.160)2. Yajing Liu, Guobing Feng, Zonghui Ma, Chen Xu, Zhuang Guo, Ping Gong*, and Liying Xu*.Synthesis and Anti-Hepatitis B Virus Evaluation of 7-Methoxy-3-heterocyclic quinolin-6-ols.  Arch. Pharm. Chem. Life Sci. (IF=1.5403. Weike Liao, Gang Hu, Zhuang Guo, Deyu Sun, Lixia Zhang, Yanxin Bu, Yingxiu Li, Yajing Liu*, Ping Gong*. Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors. Bioorg. Med. Chem. (IF=2.923)4. Yajing Liu, Zijian Liu, Jiyue Shi, Huimin Chen, Bin Mi, Peng Li and Ping Gong *. Synthesis and Cytotoxicity of Novel 10-Substituted Dihydroartemisinin Derivatives Containing N-Arylphenyl-ethenesulfonamide Groups. Molecules (IF=2.386)5.Yong Wang, Xiaoqing Sun , Di Yang, Zhuang Guo, Xuxu Fan, Minhua Nie , Feng Zhang, Yue Liu, Yue Li, Yulin Wang, Ping Gong, Yajing Liu* . Design, synthesis, and structure–activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element. Bioorg. Med. Chem. (IF=2.923)6. Ju Liu, Minhua Nie, Yanjing Wang, Jinxing Hu, Feng Zhang, Yanlin Gao, Yajing Liu**, Ping Gong*. Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors. Eur. J. of Med. Chem. (IF=3.447)专利及其他1. 宫平，赵燕芳，刘亚婧，翟鑫，李赛，朱五福，秦铭泽. 喹啉类及噌啉类化合物及其应用. PCT /CN2012/001640；中国专利号：ZL201210111920.1；美国专利号：9,382,232；日本专利号：JP6087954；欧洲专利号：2799437.2. 宫平，赵燕芳，刘亚婧，翟鑫. 新的喹啉类化合物及其用途. 国际申请号：PCT/CN2013/085848（美国：US14703769、日本：公开号2015-535265、韩国、欧洲：EP 2 915 806 A1）。台湾专利号：I473792；香港专利号：HKI130116；中国专利号：ZL201210436831.4.3. 宫平，刘亚婧，赵燕芳，翟鑫，秦铭泽. 吡啶类化合物及其用途. ZL201310253646.6.4. 宫平，赵燕芳，刘亚婧，翟鑫，唐启东.喹啉类化合物及其制备方法和应用.ZL201310101651.5.