个人简述:

关奇，男，博士，副教授。2010年毕业于沈阳药科大学，获制药工程学士学位，2015年于同校获药物化学博士学位。2017年被聘为沈阳药科大学副教授。作为课题负责人主持了国家自然科学基金青年基金项目1项、辽宁省科技厅项目1项、辽宁省教育厅项目1项、沈阳市科技计划项目1项；另外，作为项目骨干成员承担国家自然科学基金应急项目1项。目前已在Green.Chem., Cancer. Lett., Eur. J. Med. Chem., MedChemComm, Bioorg. Med. Chem.Lett., 等期刊发表论文10余篇。

科研工作:

近年来发表代表性论文
1.QiGuan,Mingyang Jiang, Junhui Wu, Yan peng Zhai, Yue Wu, Kai Bao*, Weige Zhang*.Direct cycle between co-product and reactant: an approach to improve the atomeconomy and its application in the synthesis and protection of primary amines.Green chemistry. 18(2016) 5794-5799. (IF=9.125)2.Qi Guan, Chunming Han, Daiying Zuo, Min’an Zhai,Zengqiang Li, Qian Zhang, Yanpeng Zhai, Xuewei Jiang, Kai Bao, Yingliang Wu*, WeigeZhang*. Synthesis andEvaluation of Benzimidazole Carbamates Bearing Indole Moieties forAntiproliferative and Antitubulin Activities. EuropeanJournal of Medicinal Chemistry. 2014, 87, 306-315 (IF=4.519)3.Qi Guan, Fushan Yang, Dandan Guo, Jingwen Xu,Mingyang Jiang, Chunjiang Liu, Kai Bao, Yingliang Wu*, Weige Zhang*. Synthesis and Biological Evaluation of Novel3,4-Diaryl-1,2,5-selenadiazol Analogues of Combretastatin A-4. EuropeanJournal of Medicinal Chemistry. 2014, 87, 1-9 (IF=4.519)4.Qi Guan, Zengjin Cheng, Xiaoxue Ma, Lijie Wang,Dongjie Feng, Yuanhang Cui, Kai Bao, Lan Wu*, Weige Zhang*. Synthesis andBioevaluation of 2-Phenyl-4-methyl- 1,3-selenazole-5-carboxylic Acids as PotentXanthine Oxidase Inhibitors.EuropeanJournal of Medicinal Chemistry. 2014, 85, 508-516 (IF=4.519)5.Qi Guan, Daiying Zuo, NanJiang, Huan Qi, Yanpeng Zhai, Zhaoshi Bai, Dongjie Feng, Lei Yang, MingyangJiang, Kai Bao, Chang Li, Yingliang Wu*, Weige Zhang*.Microwave-assisted Synthesis and BiologicalEvaluation of 3,4-Diaryl Maleic Anhydride/N-Substituted Maleimide Derivativesas Combretastatin A-4 Analogues. Bioorganic & MedicinalChemistry Letters. 2015, 25(3), 631-634 (IF=2.454)6.Qi Guan1, Dongjie Feng1, Zhaoshi Bai,Yuanhang Cui, Daiying Zuo, Min’an Zhai, Xuewei Jiang, Wenbo Zhou, Kai Bao, Yingliang Wu*, Weige Zhang*. Microwave-assisted Synthesis, MolecularDocking and Antiproliferative Activity of3/5-Aryl-5/3-(3,4,5-trimethoxybenzoyl)-1,2,4-oxadiazol Derivatives.Medicinal Chemistry Communications. 2015,6(8), 1484-1493 (IF=2.608)7.AilongShi, Defa Wang, He Wang, Yue Wu, Haiqiu Tian, Qi Guan*, Kai Bao*,Weige Zhang*. Synthesis and bioevaluation of 2-phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylicacid/carbohydrazide derivatives as potent xanthine oxidase inhibitors.RSCAdvances. 6 (2016) 114879-114888. (IF=3.108)