科研工作:

1、主持国家自然科学基金“铝骨病大鼠骨形成抑制的Wnt/β-catenin信号转导机制”，2014-2017,85万2、主持国家自然科学基金“铝免疫毒性的神经内分泌调控机制”，2012-2015，60万3、主持高等学校博士学科点专项科研基金“铝骨病大鼠骨形成调控的分子机制，2014-2016,12万4、主持黑龙江省级领军人才梯队后备人才项目“铝致大鼠成骨作用抑制的分子机制”，2013-2015，5万5、主持黑龙江省教育厅科学技术研究项目“铝骨病大鼠骨矿化抑制的分子机制”，2014-2016，2.5万6、主持黑龙江省自然科学基金“铝暴露致大鼠骨损伤的分子机制”，2010-2012，5万7、主持黑龙江省后背人才基金“铝暴露致大鼠骨丢失的分子机制”2013-2015，5万。近五年代表性著作、论文：1、专著李艳飞，李心慰，朱言柱，铝中毒研究，中国农业出版社，240千字，20152、通讯作者文章1.Effectsofsub-chronicaluminumexposureonserumconcentrationsofironandironassociatedproteinsinrats.BiologicalTraceElementResearch.2011,141(1-3):246-253.(SCI，通讯作者)2.EffectsofAluminumExposureonBoneMineralDensity,MineralinRats.BiolTraceElemRes.2011(143):378-385.(SCI，通讯作者)3.Dynamicanalysisofexposuretoaluminumandanacidicconditiononboneformationinyounggrowingrats.EnvironmentalToxicologyandPharmacology.2011,31(3):295-301.(SCI，通讯作者)4.EffectsofSubchronicAluminumExposureontheImmuneFunctionofErythrocytesinRats.Biologicaltraceelementresearch.2011,143(3):1576-1580.(SCI，通讯作者)5.Effectsofaluminumexposureontheallergicresponsesandhumoralimmunefunctioninrats.Biometals.2011,24:973-97.(SCI，通讯作者)6.Effectsofaluminumexposureontheadherence,chemotaxisandphagocytosiscapacityofperitonealmacrophagesinrats.BiolTraceElemRes.2011,144:1032-1038.(SCI，通讯作者)7.Effectsofaluminumexposureonserumsexhormonesandandrogenreceptorexpressioninmalerats[J].BiolTraceElemRes.2011,144:1050-1058.(SCI，通讯作者)8.SuppressiveeffectsofaluminumtrichlorideontheTlymphocyteimmunefunctionofrats.FoodandChemicalToxicology.2012,50:532-535.(SCI，通讯作者)9.EffectsofSubchronicAluminumExposureontheReproductiveFunctioninFemaleRats.BiolTraceElemRes.2012,145:382-385.(SCI，通讯作者)10.EffectsofAluminumonImmuneFunctionsofCulturedSplenicTandBLymphocytesinRats.BiolTraceElemRes.2012,147:246-250.(SCI，通讯作者)11.Effectsofaluminumtrichlorideonthetraceelementsandcytokinesinthespleenofrats.FoodandChemicalToxicology.2012,50:2911-2915.(SCI，通讯作者)12.AluminumInducesOsteoblastApoptosisThroughtheOxidativeStress-MediatedJNKSignalingPathway.BiolTraceElemRes.2012,150:502-508.(SCI，通讯作者)13.SuppressiveeffectofaccumulatedaluminumtrichlorideonthehepaticmicrosomalcytochromeP450enzymesysteminrats.FoodandChemicalToxicology.2013,51:210-214.(SCI，通讯作者)14.Impactofaluminumexposureontheimmunesystem:aminireview.EnvironmentalToxicologyandPharmacology.2013,82-87.(SCI，通讯作者)15.EffectsofNorepinephrineonImmuneFunctionsofCulturedSplenicLymphocytesExposedtoAluminumTrichloride.BiolTraceElemRes.2013,154:275-280.(SCI，通讯作者)16.EffectsofAlonthesplenicimmunefunctionandNEinrats.FoodChemToxicol.2013,62:194-198.(SCI，通讯作者)17.EffectsofSub-chronicAluminumChlorideExposureonOvaryofRats.LifeSciences.2014,(100):61-66.(SCI，通讯作者)18.Effectsofsubchronicaluminumchlorideonspermatogenesisandtesticularenzymaticactivityinmalerats.Lifesciences.2014,102:36-40.(SCI，通讯作者)19.ImmunotoxicityofAluminum.Chemosphere.2014,104(6):1-6.(SCI，通讯作者)20.Aluminumchlorideandnorepinephrineinducedimmunotoxicityonspleniclymphocytesbyactivatingβ2-AR/cAMP/PKA/NF-κBsignalpathwayinrats.BiolTraceElemRes.2014,162:168-174.(SCI，通讯作者)21.AlCl3InducesLymphocyteApoptosisinRatsthroughtheMitochondria-CaspaseDependentPathway.EnvironmentalToxicology.2015.DOI:10.1002/tox.22051.(SCI，通讯作者)22.Aluminumtrichloridedisordersbileacidsecretionandinduceshepatocyteapoptosisinrats.CellBiochemistryandBbiophysics.2015.DOI:10.1007/s12013-014-0380-z.(SCI，通讯作者)23.NEstrengthenstheimmunosuppressioninducedbyAlCl3throughβ2-AR/cAMPpathwayinculturedratperitonealmacrophages.BiolTraceElemRes.2015,164:234-241.(SCI，通讯作者)24.EffectsofAluminumChlorideontheSerumProtein,BilirubinandHepaticTraceElementsintheChickens.ToxicolIndHealth.2015,DOI:10.1177/0748233715578035.(SCI，通讯作者)25.AluminiumchlorideinducesosteoblastsapoptosisviadisruptingcalciumhomeostasisandactivatingCa2+/CaMKIIsignalpathway.BiolTraceElemRes.2015,169(2):247-253.(SCI，通讯作者)26.cAMP/PKAsignalingpathwayinducesapoptosisbyinhibitedNF-κBinaluminumchloride-treatedlymphocytesinvitro.BiolTraceElemRes.2015.DOI10.1007/s12011-015-0461-x.(SCI，通讯作者)27.AluminumchlorideInducesHypertensionandDisturbstheFunctionofErythrocyteMembraneinMaleRats.BiolTraceElemRes.2015DOI10.1007/s12011-015-0504-3.(SCI，通讯作者)28.AluminumtrichlorideimpairsboneanddownregulatesWnt/βcateninpathwayinrats.FoodandChemicalToxicology.2015,86:154-162.(SCI，通讯作者)29.AluminumchlorideinhibitsosteoblasticdifferentiationthroughinactivationofWnt/β-cateninsignalingpathwayinratosteoblasts.EnvironmentalToxicologyandPharmacology.2015,8(42):198-204.(SCI，通讯作者)30.AluminumtrichlorideinhibitsosteoblastmineralizationviaTGF-β1/Smadsignalingpathway.Chemico-BiologicalInteractions.2016,244:9-15.(SCI，通讯作者)31.Theimmunotoxicityofaluminumtrichlorideonratperitonealmacrophagesviaβ2adrenoceptors/cAMPpathway.Chemosphere.2016,149:34-40.(SCI，通讯作者)32.Aluminumchlorideinducesneuroinflammation,lossofneuronaldendriticspineandcognitionimpairmentindevelopingrat.Chemosphere.2016.DOI:org/10.1016/j.Chemosphere.2016.02.092.(SCI，通讯作者)33.TheToxicityofAluminumChlorideonKidneyofRats.BiolTraceElemRes.2016.DOI10.1007/s12011-016-064-9.(SCI，通讯作者)