科研工作:

1.国家自然科学基金重点项目项目名称：鸡脂肪组织生长的分子遗传学基础（编号：30430510），130万，本人为项目主持人，2005-2008。2.黑龙江省自然科学基金重点项目项目名称：鸡脂肪细胞分化转录因子基因的功能研究（编号：ZJN0604-01），10万，本人为项目主持人，2007-2009。完成人排序：第一3.国家973项目项目名称：猪、鸡重要经济性状遗传的分子机制（No.2006CB102100）。课题名称：重要复杂性状的比较基因组（No.2006CB102105），课题总经费383万元，本人经费96万元，本人为课题第二主持人，2006-2010。4.国家863重大项目项目名称：主要动植物功能基因组研究。课题名称：家鸡重要经济性状功能基因组研究（2006AA10A120），课题总经费565万元，本人经费115万元，本人为课题副主持人，2006-2010。5.国家转基因生物新品种培育重大专项课题课题名称：高通量基因克隆技术体系的研究（2008ZX08009-002）；任务名称：影响猪、牛、羊生长与肉质等性状的功能基因的高通量克隆鉴定技术；子任务名称：羊毛品质性状关键基因的高通量筛选和克隆，76万元，本人为子任务主持人，2008-2011。6.国家现代农业产业技术体系建设项目项目名称：国家肉鸡产业技术体系(No.CARS-42)，210万元，本人为岗位专家，2008-2010。7.国家高技术研究发展计划（863）项目子课题项目名称：主要动植物功能基因组研究课题名称：优质速长型白羽黄鸡全基因组选择育种研究（编号：2010AA10A102）,21万元，本人为课题子任务负责人，2010-2011。8.黑龙江省高等学校科技创新团队建设计划项目团队名称：家禽遗传育种创新团队；项目名称：鸡生长和体组成性状的功能基因组，200万元，本人为团队负责人和项目主持人，2010-2013。9.国家现代农业产业技术体系建设项目项目名称：国家肉鸡产业技术体系(No.CARS-42)，350万元，本人为岗位专家，2011-2015。10.国家高技术研究发展计划（863）项目项目名称：鸡重要经济性状的功能基因组学研究(2013AA102501)，1028万，本人为课题主持人，2013-2017。近五年代表性著作、论文：st1:*{behavior:url(#ieooui) /*StyleDefinitions*/table.MsoNormalTable{mso-style-name:普通表格mso-tstyle-rowband-size:0mso-tstyle-colband-size:0mso-style-noshow:yesmso-style-parent:""mso-padding-alt:0cm5.4pt0cm5.4ptmso-para-margin:0cmmso-para-margin-bottom:.0001ptmso-pagination:widow-orphanfont-size:10.0ptfont-family:"TimesNewRoman"mso-fareast-font-family:"TimesNewRoman"mso-ansi-language:#0400mso-fareast-language:#0400mso-bidi-language:#0400 208.NingDing,YuanGao,NingWang,HuiLi.FunctionalanalysisofthechickenPPARγgene5′-flankingregionandC/EBPα-mediatedgeneregulation.ComparativeBiochemistryandPhysiology,PartB,2011,158,297-303.210.JingYao,YuxiangWang,WeishiWang,NingWang,andHuiLi.Solexasequencinganalysisofchickenpre-adipocytemicroRNAs.Biosci.Biotechnol.Biochem.,2011,75(1):54-61.216.H.Zhang,S.H.Liu,Q.Zhang,Y.D.Zhang,S.Z.Wang,Q.G.Wang,Y.X.Wang,Z.Q.Tang&H.Li.Fine-mappingofquantitativetraitlociforbodyweightandbonetraitsandpositionalcloningoftheRB1geneinchicken.J.Anim.Breed.Genet.2011,128:366–375.217.H.Shi,Q.Zhang,Y.Wang,P.Yang,Q.Wang,andH.Li.Chickenadipocytefattyacid-bindingproteinknockdownaffectsexpressionofperoxisomeproliferator-activatedreceptorγgeneduringoleate-inducedadipocytedifferentiation.PoultryScience,2011,90:1037-1044.220．L.Guo,B.Sun,Z.Shang,L.Leng,Y.Wang,N.Wang,andH.Li.Comparisonofadiposetissuecellularityinchickenlinesdivergentlyselectedforfatness.PoultryScience,2011,90:2024-2034.226.S.Z.Wang,X.X.Hu,Z.P.Wang,X.C.Li,Q.G.Wang,Y.X.Wang,Z.Q.TangandH.Li.Quantitativetraitlociassociatedwithbodyweightandabdominalfattraitsonchickenchromosomes3,5and7.GeneticsandMolecularResearch,2012,11(2):956-965.230.HuiZhang,XiaoxiangHu,ZhipengWang,YuandanZhang,ShouzhiWang,NingWang,LiMa,LiLeng,ShengwenWang,QiguiWang,YuxiangWang,ZhiquanTang,NingLi,YangDa,HuiLi.SelectionSignatureAnalysisImplicatesthePC1/PCSK1RegionforChickenAbdominalFatContent.PLoSONE,20127(7):e40736.238.HuiZhang,Shou-ZhiWang,Zhi-PengWang,YangDa,NingWang,Xiao-XiangHu,Yuan-DanZhang,Yu-XiangWang,LiLeng,Zhi-QuanTangandHuiLi.Agenome-widescanofselectivesweepsintwobroilerchickenlinesdivergentlyselectedforabdominalfatcontent.BMCGenomics,2012,13:704.254.ZhiweiZhang,HaixiaWang,YingningSun,HuiLi,andNingWang.Klf7modulatesthedifferentiationandproliferationofchickenpreadipocyte.ActaBiochimBiophysSin2013,45:280–288.（王宁和李辉为通讯作者）258.Zhi-WeiZHANG,Zhi-PengWANG,KunZHANG,NingWANGandHuiLI.Cloning,tissueexpressionandpolymorphismsofchickenKrüppel-likefactor7gene.AnimalScienceJournal,2013,84:535–542.（李辉为通讯作者）259.Q.Zhang,H.Shi,W.Liu,Y.Wang,Q.WangandH.Li.DifferentialexpressionofL-FABPandL-BABPbetweenfatandleanchickens.Genet.Mol.Res.,2013,12(4):4192-4206.（李辉和王启贵为通讯作者）260.YufangZhao,EnguangRong,ShouzhiWang,HuiZhang,LiLeng,YuxiangWang,QiguiWangandHuiLi.IdentificationofSNPsoftheL-BABPandL-FABPandtheirAssociationwithGrowthandBodyCompositionTraitsinChicken.J.Poult.Sci.,2013,50:300-310.（李辉、王启贵为通讯作者）262.FanggeLi,GuoHu,HuiZhang,ShouzhiWang,ZhipengWangandHuiLi.EpistaticEffectsonAbdominalFatContentinChickens:ResultsfromaGenome-WideSNP-SNPInteractionAnalysis.PLoSONE,2013,8(12):e81520.（李辉为通讯作者）268.ZhouchunSHANG,LinGUO,NingWANG,HuiSHI,YuxiangWANGandHuiLI.Oleatepromotesdifferentiationofchickenprimarypreadipocytesinvitro.Biosci.Rep.,2014,34(1):51-57.（李辉为通讯作者）270.S.J.Liu,J.L.LiandH.Li.AdiagnosticmethodforganderselectioninZigeese(AnsercygnoidesL.)andRhingeese(AnseranserL.)usingmassagereactionandsemenquality.AnimalProductionScience,2014,54,569–573.（李辉为通讯作者）271.Hui-Zhang,Zhi-QiangDu,Jia-QiangDong,Hai-XiaWang,Hong-YanShi,NingWang,Shou-ZhiWangandHuiLi.Detectionofgenome-widecopynumbervariationsintwochickenlinesdivergentlyselectedforabdominalfatcontent.BMCGenomics,2014,15(1):1-12.（李辉为通讯作者）272.Zhi-WeiZhang,Chun-YanWu,HuiLiandNingWang.ExpressionandfunctionalanalysesofKrüppel-likefactor3inchickenadiposetissue.Bioscience,Biotechnology,andBiochemistry,2014,78(4):614–623.（王宁、李辉为通讯作者）273.Z.W.Zhang,E.G.Rong,M.X.Shi,C.Y.Wu,B.Sun,Y.X.Wang,N.Wang,andH.Li.ExpressionandfunctionalanalysisofKrüppel-likefactor2inchickenadiposetissue.J.Anim.Sci.,2014.92:4797–4805.（李辉、王宁为通讯作者）274.ZhipengWang,HuiZhang,HuaYang,ShouzhiWang,EnguangRong,WenyuPei,HuiLi,NingWang.Genome-WideAssociationStudyforWoolProductionTraitsinaChineseMerinoSheepPopulation.PLoSONE,2014,9(9):e107101.（王宁、李辉为通讯作者）275.Q.He,S.Z.Wang,L.Leng,W.Na,Q.G.Wang,andH.Li.Differentiallyexpressedgenesintheliverofleanandfatchickens.GeneticsandMolecularResearch,2014,13(4):10823-10828.（李辉、王启贵为通讯作者）299.GaoGL,NaW,WangYX,ZhangHF,LiH,WangQG.Roleofaliverfattyacid-bindingproteingeneinlipidmetabolisminchickenhepatocytes.GenetMolRes.,2015,14(2):4847-4857.300.WangQG,ZhangHF,WangSZ,GaoGL,LengL,NaW,LiH.MicroarrayanalysisofdifferentiallyexpressedgenesintheliverbetweenBai'erlayersandbroilers.GenetMolRes.,2015,14(1):2885-2889.301.WangW,DuZQ,ChengB,WangY,YaoJ,LiY,CaoZ,LuanP,WangN,LiH.ExpressionprofilingofpreadipocytemicroRNAsbydeepsequencingonchickenlinesdivergentlyselectedforabdominalfatness.PLoSOne,2015,10(2):e0117843.302.DongJ-Q,ZhangHui,JiangX-F,WangS-Z,LengL,CaoZ-P,LiY-M,LuanP,LiH.Comparisonofserumbiochemicalparametersbetweentwobroilerchickenlinesdivergentlyselectedforabdominalfatcontent.J.Anim.Sci.,2015,93(7):3278-86.303.GaoY,SunY,DuanK,ShiH,WangS,LiH,WangN.CpGsiteDNAmethylationoftheCCAAT/enhancer-bindingprotein,alphapromoterinchickenlinesdivergentlyselectedforfatness.AnimGenet.2015Aug46(4):410-7.304.LiangMJ,WangZP,XuL,LengL,WangSZ,LuanP,CaoZP,LiYM,LiH.Estimatesofgeneticparametersforliverfattraitsinbroilerlinesdivergentlyselectedforabdominalfat.GenetMolRes.,2015,14(3):9646-54.305.JingPC，WuX,XuS,ZhangH,LiY,CaoZ,LiH,WangS.Differentialexpressionofsixgenesandcorrelationwithfatnesstraitsinauniquebroilerpopulation.SaudiJournalofBiologicalSciences,doi:10.1016/j.sjbs.2015.04.014.307.DuanK,SunY,ZhangX,ZhangT,ZhangW,ZhangJ,WangG,WangS,LengL,LiH,WangN.Identificationandcharacterizationoftranscriptvariantsofchickenperoxisomeproliferator-activatedreceptorgamma.PoultSci.,2015,94(10):2516-27.309.XianwenWu,QiZhang,SongsongXu,PengchengJin,PengLuan,YumaoLi,ZhipingCao,LiLeng,YuxiangWang,ShouzhiWang.Differentialexpressionofsixchickengenesassociatedwithfatnesstraitsinadivergentlyselectedbroilerpopulation.MolCellProbes,2016,30(1):1-5.310.B.H.Cheng,L.Leng,M.Q.Wu,Q.Zhang,X.Y.Zhang,S.S.Xu,Z.P.Cao,Y.M.Li,P.Luan,H.Li.Expressionanalysisofbonemorphogeneticprotein4betweenfatandleanbirdsinadiposetissueandserum.DomesticAnimalEndocrinology,2016,56:13–19.