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Artificial Intelligence in Medicine publishes original articles from a wide variety of interdisciplinary perspectives concerning the theory and practice of artificial intelligence (AI) in medicine, medically-oriented human biology, and health care. Artificial intelligence in medicine may be characterized as the scientific discipline pertaining to research studies, projects, and applications that aim at supporting decision-based medical tasks through knowledge- and/or data-intensive computer-based solutions that ultimately support and improve the performance of a human care provider. Artificial Intelligence in Medicine considers for publication manuscripts that have both: • Potential high impact in some medical or healthcare domain; • Strong novelty of method and theory related to AI and computer science techniques. Artificial Intelligence in Medicine papers must refer to real-world medical domains, considered and discussed at the proper depth, from both the technical and the medical points of view. The inclusion of a clinical assessment of the usefulness and potential impact of the submitted work is strongly recommended.