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This interdisciplinary journal provides a forum for presenting new ideas in continuum and quasi-continuum modeling of systems with a large number of degrees of freedom and sufficient complexity to require thermodynamic closure. Major emphasis is placed on papers attempting to bridge the gap between discrete and continuum approaches as well as micro- and macro-scales, by means of homogenization, statistical averaging and other mathematical tools aimed at the judicial elimination of small time and length scales. The journal is particularly interested in contributions focusing on a simultaneous description of complex systems at several disparate scales. Papers presenting and explaining new experimental findings are highly encouraged. The journal welcomes numerical studies aimed at understanding the physical nature of the phenomena.